Esophageal & Gastric  Cancers







March 2009 from Annals of Surgery: Study showing Omega-3 EPA preserved muscle mass by reducing inflammation.

"...we do not expect these findings are unique to cancer surgery, and similar benefits may accrue to patients needing complex surgical care for non-cancer problems, for instance liver transplantation or major cardiac surgery.



February 2008

"For patients with kidney cancer or gastrointestinal stromal tumors (GIST) treated with sunitinib (Sutent), the heart failure risk in real-world use may be higher than expected, researchers said here". ASCO GU meeting

Telli ML, et al "Cardiotoxicity associated with the cancer therapeutic agent sunitinib malate" ASCO GU Meeting 2008.

www.medpagetoday.com

Nutrient Intake and Esophageal Cancer in the Caspian Littoral of Iran: A Case-Control Study Fereydoun Siassi PhD,Zahra Pouransari MD, and Parviz Ghadirian, PhD

Address all correspondence and reprint requests to: Parviz Ghadirian, PhD, Epidemiology Research Unit, Research Centre, CHUM, HotelDieu, 3850 St. Urhain Street, Montreal, Quebec H2W 1T8, Canada.

ABSTRACT: The purpose of this study was to investigate the possible contribution of different dietary nutrients in the development of esophageal cancer (EC) in the Caspian littoral of Iran. Forty-one cases and 145 members of their households were matched for age and gender with 40 non-blood-relative controls and 130 members of their households for their nutrient intake. A standard 24-hour dietary recall questionnaire was used to estimate the daily intake of energy, protein, P, Fe, Na, K, vitamins C and A, thiamin, riboflavin, and niacin.

Dietary nutrient deficiency was defined as less than 75% of the World Health Organization human nutritional requirements, except for P, Na, and K, for which the United States Recommended Dietary Allowances were followed.

The results indicate the following: (1) The mean daily intake of all nutrients, except for riboflavin, was significantly lower in cases than in control subjects (P < .05); (2) with the exception of protein, riboflavin, and phosphorus, significant correlation was observed between the pattern of nutrient intake and health status of the study subjects (P < .05); and (3) dietary deficiency of niacin and phosphorus was associated significantly with the risk of EC development among case and control households (P < .01-.001), indicating that persons living in case households with dietary deficiencies of these nutrients have more than twice the risk of developing EC tumors than those living in control households.

In conclusion, apparently some nutrients, such as P and niacin, may play a role in the etiology of esophageal cancer, and the status of these nutrients may be used eventually as an epidemiologic predictive marker for EC in the Caspian littoral of Iran and perhaps other regions.

Ann's NOTE: Just another 'bead' on the chain of evidence for patients on the importance of nutrients from foods.


Nutrients & Risk of Subtypes of Esoph/Gastric Ca

Cancer Epidemiology, Biomarkers & Prevention, 10/01

Nutrition & Pharyngeal Cancer
Depth of Tumor Invasion a Factor
Diet & Oral, Pharyngeal & Esophageal Ca
Selenomethionine Protects: Esophageal Squamous Cell Ca
"Dietary Patterns & Risk of Incident Gastric Adenocarcinoma,"
Broccoli Sprouts May Protect Against Gastric Cancer
Dietary Protective & Risk Factors (China)

Jpn J Cancer Res, 11/01

Vegetables, Fruit & Risk of Gastric Ca (Japan)
Dietary Risk Factors:Upper Aerodigestive Ca
Mediterranean Diet & Risk:Upper Aerodigestive Tract
Cruciferous Veg/Mushrooms & GI Ca Risk
Red Meat Linked to Stomach & Esoph Ca

Am J Clinical Nutrition, 12/01

Bacteriostatic effect of dill, fennel, caraway & cinnamon extracts against Helicobacter pylori

J Nutritional & Env Med, June 2005

Dietary Patterns & Adenocarcinoma Esophagus/Distal Stomach

Am J Clin Nutr 1/02

Bacteria and Stomach Cancer: Study

Gastroenterology and Am J of Physiology,1/02

H. pylori & Gastric Ca:STRONG Connection
Natural Honey Prevents Some Gastric Lesions
Helicobacter Pylori, Triple Therapy and Cranberry Juice
Various Vitamins and Stomach Cancer Mortality (US)

Cancer Epidemiology Biomarkers & Prevention, 1/02

Gleevec, Vit C and Insulin Slow GIST in a Patient
Higher Levels of Vit C & Reduced Gastric Ca Risk
Oxaliplatin, Neurotoxicity, Calcium, Magnesium
Acupuncture Relieves Xerostomia

Cancer, 2002

Immunonutrition Improves Gastric Ca Surgery

Gastroenterology, 6/02

Augment RTx with Nutritional Support
Peppermint Oil Inhibits GI Spasms

Gastrointest Endosc., 4/03

Patient Experiences/Expectations After Esophageal Surgery

Eur J Cancer Care, 9/06

Plasma DNA level reliable marker recurrent esophageal ca
Omega-3 EPA preserves muscle mass AFTER Surgery
Green Tea:Prevent Oral Ca in Smokers

AACR Abstract #4803,2003

Nutritional Intervention BENEFICIAL With Radiotherapy

Brit J Cancer, 6/04

Nutrition Support Improves Patient Outcome:Esophageal Ca
Gastric/Aerodigestive Ca Abstracts

Frontiers in Cancer Prevention Research, 2003

Changes:Gene Expression/Intermed Endpoints:Gastric
Orange Peel Extract/Intestinal Tumors (Mice)
Resveratrol in Intestinal Epithelial Cells & Humans
Gastric Surgery Associated with Risk of Laryngeal Cancer

Annals of Surgery, 11/04

Ginkgo biloba Inhibits Gastric Ca Cell Growth

World J Gastroenterology,

LarynxLink

Link to comprehensive source for laryngectomee and larynx cancer information, and laryngectomee rehabilitation resources

Marrow Cells Spawn Stomach Cancers

Nature, 11/04

After Surgery Feeding w/Omega-3 Esophageal Cancer

J Parenter Enteral Nutr, 5-6/05

Study: Eat Normally After Esophageal Surgery
Omega-3 EPA preserves muscle mass AFTER Surgery
Bone disorder and vitamin D after gastric cancer surgery

Hepatogastroenterology, Jul-Aug, 2007

Complications of a Gastrostomy Tube
Chinese Herbs of Shenghe Powder Reverse Multidrug Resistance of Gastric Carcinoma

Integrative Cancer Therapies, Decmber 2007

GIST specific

articles

Sunitinib Can Have Toxic Effects on Heart
Gleevec, Vit C and Insulin Slow GIST in a Patient
GIST: Epidemiologic, health-related QoL & economic burden
Long-term Outcomes Laparoscopic Resection GIST
Osteopathic support for a survivor of gastric cancer

International Journal of Osteopathic Medicine, published online June 2008

Osteopathy
Radiofrequency Ablation (RFA):  Barrett's esophagus

Gastroenterology meeting May, 2008 San Diego, CA

Her2 testing in gastric cancer

Pathologe. 2010 May;31(3):208-17.PMID: 20443098 [PubMed - in process]

Frank C. Garland: Esophageal Cancer 2010

New York Times, Sept 2010


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